BDBM359108 US10220048, Compound AA18::US10952992, No. AA18::US11413242, Compound AA18::US11666558, Example AA18

SMILES CCOC(=O)c1csc(n1)[C@H](Cc1ccc(NS(O)(=O)=O)cc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OC

InChI Key InChIKey=NHUVSMIKOFOWMO-PMACEKPBSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 359108   

TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Aerpio Therapeutics

US Patent
LigandPNGBDBM359108(US10220048, Compound AA18 | US10952992, No. AA18 |...)
Affinity DataIC50:  0.200nMAssay Description:HPTP-β inhibition can be tested by any method chosen by the formulator, for example, Amarasinge K. K. et al., “Design and Synthesis of Potent, N...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Aerpio Therapeutics

US Patent
LigandPNGBDBM359108(US10220048, Compound AA18 | US10952992, No. AA18 |...)
Affinity DataIC50:  0.200nMAssay Description:Non-limiting examples of the HPTP-β IC50(μM) activity for illustrative compounds are listed in TABLE 2.More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Aerpio Therapeutics

US Patent
LigandPNGBDBM359108(US10220048, Compound AA18 | US10952992, No. AA18 |...)
Affinity DataIC50:  0.200nMAssay Description:Non-limiting examples of the HPTPβ IC50 (μM) activity.More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Aerpio Therapeutics

US Patent
LigandPNGBDBM359108(US10220048, Compound AA18 | US10952992, No. AA18 |...)
Affinity DataIC50:  0.200nMAssay Description:Non-limiting examples of the HPTP-β IC50 (μM) activity.More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent