BDBM363064 (R)-2-(2-(3-cyanobenzyloxy)-4-(3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-methylbenzyloxy)-6-methylbenzylamino)-3-hydroxy-2-methylpropanoic acid::US9850225, Example 1001

SMILES Cc1cc(OCc2cccc(c2C)-c2ccc3OCCOc3c2)cc(OCc2cccc(c2)C#N)c1CN[C@](C)(CO)C(O)=O

InChI Key InChIKey=YMYDEJCKLQRBRC-PSXMRANNSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 363064   

TargetProgrammed cell death 1 ligand 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM363064((R)-2-(2-(3-cyanobenzyloxy)-4-(3-(2,3-dihydrobenzo...)
Affinity DataIC50:  2.25nMAssay Description:The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent