BDBM365027 4-(3-(4-chlorobenzyl)-4,5- dihydro-3H-1,2,2a1,5- tetraazaacenaphthylen-7-yl)- N-(1-methyl-1H-pyrazol-5- yl)pyrimidin-2-amine::US10278975, Compound I-5 R::US11376260, Example I-5S::US9867833, Compound I-5(S)
SMILES Cn1nccc1Nc1nccc(n1)-c1cc2NC[C@H](Cc3ccc(Cl)cc3)c3nnc(c1)n23
InChI Key InChIKey=HSRHNPJBGFAREY-INIZCTEOSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 365027
Affinity DataIC50: 0.408nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Affinity DataIC50: <0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Affinity DataIC50: <0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair