BDBM365147 4-(3-benzyl-4-methyl-3,4- dihydro-5-oxa-1,2,2a1- triazaacenaphthylen-7-yl)-N- (1-methyl-1H-pyrazol-5- yl)pyrimidin-2-amine::US10278975, Compound I-72 3S-4R::US11376260, Example I-763R::US9867833, Compound I-72(3S,4R)
SMILES C[C@H]1Oc2cc(cc3nnc([C@@H]1Cc1ccccc1)n23)-c1ccnc(Nc2ccnn2C)n1
InChI Key InChIKey=SGEUXVVXMIAVCA-CRAIPNDOSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 365147
Affinity DataIC50: 1.56nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Affinity DataIC50: <0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Affinity DataIC50: 1.55nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair