BDBM36686 Dansyl derivative, 9L::Dansyltyrosine deriviative 3B

SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)Oc1ccc(C[C@H](NS(=O)(=O)c2cc(Br)c(Br)s2)C(O)=O)cc1

InChI Key InChIKey=PEHKVGPJOFOJHZ-FQEVSTJZSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 36686   

TargetThymidylate synthase(Lactobacillus casei)
Università

LigandPNGBDBM36686(Dansyl derivative, 9L | Dansyltyrosine deriviative...)
Affinity DataKi:  2.70E+4nMAssay Description:All compounds were screened for inhibitory activity against Lactobacillus casei thymidylate synthase (LcTS) and Escherichia coli thymidylate synthase...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Escherichia coli)
Università

LigandPNGBDBM36686(Dansyl derivative, 9L | Dansyltyrosine deriviative...)
Affinity DataKi: >1.33E+6nMAssay Description:All compounds were screened for inhibitory activity against Lactobacillus casei thymidylate synthase (LcTS) and Escherichia coli thymidylate synthase...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
Università

LigandPNGBDBM36686(Dansyl derivative, 9L | Dansyltyrosine deriviative...)
Affinity DataIC50:  1.09E+5nMpH: 7.4 T: 2°CAssay Description:The enzyme assay were performed spectrophotometrically by following the absorbance at 340nm using a hewlett Packard 8453 UV spectrophotometer equippe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed