BDBM36696 Dansyl derivative, 5L::Dansyltyrosine deriviative 13B

SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)Oc1ccc(C[C@H](NS(=O)(=O)c2ccc(cc2N(=O)=O)C(F)(F)F)C(O)=O)cc1

InChI Key InChIKey=QHAIMOJHYNFYOT-QFIPXVFZSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 36696   

TargetThymidylate synthase(Lactobacillus casei)
Università

LigandPNGBDBM36696(Dansyl derivative, 5L | Dansyltyrosine deriviative...)
Affinity DataKi:  6.70E+3nMAssay Description:All compounds were screened for inhibitory activity against Lactobacillus casei thymidylate synthase (LcTS) and Escherichia coli thymidylate synthase...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Escherichia coli)
Università

LigandPNGBDBM36696(Dansyl derivative, 5L | Dansyltyrosine deriviative...)
Affinity DataKi: >6.36E+5nMAssay Description:All compounds were screened for inhibitory activity against Lactobacillus casei thymidylate synthase (LcTS) and Escherichia coli thymidylate synthase...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
Università

LigandPNGBDBM36696(Dansyl derivative, 5L | Dansyltyrosine deriviative...)
Affinity DataIC50:  2.70E+4nMpH: 7.4 T: 2°CAssay Description:The enzyme assay were performed spectrophotometrically by following the absorbance at 340nm using a hewlett Packard 8453 UV spectrophotometer equippe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed