BDBM373089 1-biphenyl-2-yl-3- (3-methyl-1-phenyl- 1H-pyrazol-5- yl)urea::US9896447, Compound 6

SMILES Cc1cc(NC(=O)Nc2ccccc2-c2ccccc2)n(n1)-c1ccccc1

InChI Key InChIKey=OEUAAERLJRDCHK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 373089   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM373089(1-biphenyl-2-yl-3- (3-methyl-1-phenyl- 1H-pyrazol-...)
Affinity DataIC50:  420nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent