BDBM373099 1-naphthalen-1-yl-3- (6- phenylimidazo[2,1- b][1,3]thiazol-5- yl)urea::US9896447, Compound 16

SMILES O=C(Nc1c(nc2sccn12)-c1ccccc1)Nc1cccc2ccccc12

InChI Key InChIKey=WKSLGOGWMSITFF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 373099   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM373099(1-naphthalen-1-yl-3- (6- phenylimidazo[2,1- b][1,3...)
Affinity DataIC50:  290nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent