BDBM373127 1-[5-fluoro-2- (trifluoromethyl) benzyl]-3-(2-methyl- 4- phenylpyrimidin-5- yl)urea::US9896447, Compound 43

SMILES Cc1ncc(NC(=O)NCc2cc(F)ccc2C(F)(F)F)c(n1)-c1ccccc1

InChI Key InChIKey=YRUDWLLOAMMPDL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 373127   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM373127(1-[5-fluoro-2- (trifluoromethyl) benzyl]-3-(2-meth...)
Affinity DataIC50:  1.40E+3nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent