BDBM380478 US9926306, ID 183-84
SMILES Cc1cs\c(=N/C2CCCCC2)n1\N=C\c1cc(O)c(O)c(O)c1
InChI Key InChIKey=BKHGWSRXPKXSQY-LDRVEFRDSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 380478
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
University Of Maryland
Curated by ChEMBL
University Of Maryland
Curated by ChEMBL
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of FITC-BID BH3 peptide binding to recombinant GST-tagged N-terminal/C-terminal truncated Mcl-1 (unknown origin) expressed in Escherichia ...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Dana-Farber Cancer Institute
US Patent
Dana-Farber Cancer Institute
US Patent
Affinity DataIC50: 13nMAssay Description:A high-throughput competitive fluorescence polarization (FP) screening assay (Z-factor, 0.62) was developed based on the direct binding interaction b...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of FITC-BID BH3 peptide binding to recombinant GST-tagged C-terminal truncated Bcl-xL (unknown origin) expressed in Escherichia coli BL21 ...More data for this Ligand-Target Pair