BDBM383227 4-(3-(4-chloro-3- fluorobenzyl)-4,5-dihydro- 3H-1,2,2a1,5- tetraazaacenaphthylen-7-yl)- N-(1-methyl-1H-pyrazol-5- yl)pyrimidin-2-amine::US10278975, Compound I-14 S::US11376260, Example I-14S
SMILES Cn1nccc1Nc1nccc(n1)-c1cc2NC[C@H](Cc3ccc(Cl)c(F)c3)c3nnc(c1)n23
InChI Key InChIKey=ONTYTFWHLKAMFE-HNNXBMFYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 383227
Affinity DataIC50: <0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Affinity DataIC50: <0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair