BDBM383365 4-(3-(3-methoxybenzyl)-3,4- dihydro-5-oxa-1,2,2a1- triazaacenaphthylen-7-yl)-N- (1-methyl-1H-pyrazol-5- yl)pyridin-2-amine::US10278975, Compound I-97 S::US11376260, Example I-97R

SMILES COc1cccc(C[C@H]2COc3cc(cc4nnc2n34)-c2ccnc(Nc3ccnn3C)c2)c1

InChI Key InChIKey=PIKPCZAAYCLJKF-IBGZPJMESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 383365   

TargetMitogen-activated protein kinase 6(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM383365(4-(3-(3-methoxybenzyl)-3,4- dihydro-5-oxa-1,2,2a1-...)
Affinity DataIC50: <0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM383365(4-(3-(3-methoxybenzyl)-3,4- dihydro-5-oxa-1,2,2a1-...)
Affinity DataIC50:  0.794nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent