BDBM384827 2-(dimethylamino)-N-{(R)-(1- methylcyclopropyl)[4- (trifluoromethyl)phenyl]methyl}-6- oxo-1,6-dihydropyrimidine-4- carboxamide::US10285989, Example 43

SMILES CN(C)c1nc(cc(=O)[nH]1)C(=O)N[C@@H](c1ccc(cc1)C(F)(F)F)C1(C)CC1

InChI Key

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 384827   

TargetPhosphodiesterase(Rhesus macaque)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM384827(2-(dimethylamino)-N-{(R)-(1- methylcyclopropyl)[4-...)
Affinity DataKi:  0.230nMAssay Description:The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluorescence polarization...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM384827(2-(dimethylamino)-N-{(R)-(1- methylcyclopropyl)[4-...)
Affinity DataKi:  0.320nMAssay Description:The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluorescence polarization...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent