BDBM393886 US10597367, Example 183::US9969726, Example 183
SMILES Ic1ccc2N=C(CC(=O)Nc2c1)c1ccnc(c1)C#N
InChI Key InChIKey=YXDVIVMXOZYYSA-UHFFFAOYSA-N
Data 8 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 393886
TargetMetabotropic glutamate receptor 2(Rattus norvegicus)
Sanford-Burnham Medical Research Institute
US Patent
Sanford-Burnham Medical Research Institute
US Patent
Affinity DataEC50: 110nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Rattus norvegicus)
Sanford-Burnham Medical Research Institute
US Patent
Sanford-Burnham Medical Research Institute
US Patent
Affinity DataEC50: 30nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Sanford-Burnham Medical Research Institute
US Patent
Sanford-Burnham Medical Research Institute
US Patent
Affinity DataEC50: 70nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Affinity DataEC50: 160nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Rattus norvegicus)
Sanford-Burnham Medical Research Institute
US Patent
Sanford-Burnham Medical Research Institute
US Patent
Affinity DataEC50: 110nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Rattus norvegicus)
Sanford-Burnham Medical Research Institute
US Patent
Sanford-Burnham Medical Research Institute
US Patent
Affinity DataEC50: 30nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Affinity DataEC50: 70nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Sanford-Burnham Medical Research Institute
US Patent
Sanford-Burnham Medical Research Institute
US Patent
Affinity DataEC50: 160nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair