BDBM393886 US10597367, Example 183::US9969726, Example 183

SMILES Ic1ccc2N=C(CC(=O)Nc2c1)c1ccnc(c1)C#N

InChI Key InChIKey=YXDVIVMXOZYYSA-UHFFFAOYSA-N

Data  8 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 393886   

TargetMetabotropic glutamate receptor 2(Rattus norvegicus)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM393886(US10597367, Example 183 | US9969726, Example 183)
Affinity DataEC50:  110nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Rattus norvegicus)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM393886(US10597367, Example 183 | US9969726, Example 183)
Affinity DataEC50:  30nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM393886(US10597367, Example 183 | US9969726, Example 183)
Affinity DataEC50:  70nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM393886(US10597367, Example 183 | US9969726, Example 183)
Affinity DataEC50:  160nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Rattus norvegicus)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM393886(US10597367, Example 183 | US9969726, Example 183)
Affinity DataEC50:  110nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Rattus norvegicus)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM393886(US10597367, Example 183 | US9969726, Example 183)
Affinity DataEC50:  30nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM393886(US10597367, Example 183 | US9969726, Example 183)
Affinity DataEC50:  70nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM393886(US10597367, Example 183 | US9969726, Example 183)
Affinity DataEC50:  160nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent