BDBM395070 US10308615, Example 81::[4-fluoro-3- (trifluoromethyl) phenyl]{2- [(pyridin-3- ylmethyl)amino] pyrimidin-5- yl}methanone

SMILES Fc1ccc(cc1C(F)(F)F)C(=O)c1cnc(NCc2cccnc2)nc1

InChI Key InChIKey=OIUSSRUDUJXLNH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 395070   

TargetPantetheinase(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM395070(US10308615, Example 81 | [4-fluoro-3- (trifluorome...)
Affinity DataIC50: >16.9nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPantetheinase(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM395070(US10308615, Example 81 | [4-fluoro-3- (trifluorome...)
Affinity DataIC50:  3.40nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent