BDBM399931 3-(4-Cyano-3-fluorophenyl)-N-cyclopropyl-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine-2-carboxamide ::US10323042, Example 11::US10738063, Example 11
SMILES Fc1cc(ccc1C#N)-c1c2OCCCn2nc1C(=O)NC1CC1
InChI Key InChIKey=RQCIGHZUMYJCCJ-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 399931
Affinity DataIC50: 972nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
TargetIsoform 7 of cAMP-specific 3',5'-cyclic phosphodiesterase 4A (PDE4A8)(Homo sapiens (Human))
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 164nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Affinity DataIC50: 284nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
TargetIsoform 3 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D (hPDE4D3)(Homo sapiens (Human))
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: >3.00E+4nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair