BDBM415703 US10442759, Compound I-15

SMILES CCOc1ccc(cc1)C(Oc1ccc(N(CC(O)=O)S(=O)(=O)c2c(C)cc(C)cc2C)c2ccccc12)C(O)=O

InChI Key InChIKey=BYDRCKDNJKPUKF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 415703   

TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM415703(US10442759, Compound I-15)
Affinity DataIC50:  150nMAssay Description:Inhibition of Keap1-Nrf2 (unknown origin) protein-protein interactionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1/Nuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
China Pharmaceutical University

US Patent
LigandPNGBDBM415703(US10442759, Compound I-15)
Affinity DataIC50:  84nMAssay Description:The instrument used in the FP experiment was the SpectraMax Multi-Mode Microplate Reader (Molecular Devices), and the excitation and emission wavelen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent