BDBM4196 1,8-Naphthyridin-2(1H)-one deriv. 9h::3-(2,6-Dichlorophenyl)-1-methyl-7-[[3-(4-methylpiperazinyl)propyl]amino]-1,8-naphthyridin-2(1H)-one::3-(2,6-dichlorophenyl)-1-methyl-7-{[3-(4-methylpiperazin-1-yl)propyl]amino}-1,2-dihydro-1,8-naphthyridin-2-one

SMILES CN1CCN(CCCNc2ccc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)CC1

InChI Key InChIKey=ALESBZWZJZPACS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 4196   

TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM4196(1,8-Naphthyridin-2(1H)-one deriv. 9h | 3-(2,6-Dich...)
Affinity DataIC50: >5.00E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM4196(1,8-Naphthyridin-2(1H)-one deriv. 9h | 3-(2,6-Dich...)
Affinity DataIC50: >5.00E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM4196(1,8-Naphthyridin-2(1H)-one deriv. 9h | 3-(2,6-Dich...)
Affinity DataIC50: >5.00E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed