BDBM420240 US10485800, Cmpd ID Preparation of 1-(4-(4-(3-(1H-indol-5-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl)benzyl)-2-methylpiperazin-1-yl)ethanone ::US10485800, Example 188

SMILES CC1CN(Cc2ccc(cc2)-c2cnc3[nH]cc(-c4ccc5[nH]ccc5c4)c3c2)CCN1C(C)=O

InChI Key InChIKey=TXDABLBRNBWKPD-SLEBQGDGSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 420240   

TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
The University of Rochester

US Patent
LigandPNGBDBM420240(US10485800, Cmpd ID Preparation of 1-(4-(4-(3-(1H-...)
Affinity DataIC50: <100nMAssay Description:200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent