BDBM431882 US10550114, Compound 46

SMILES Cn1c2ccc(NC(=O)C=C)cc2n(C2CCN(Cc3ccc(cc3)-c3nc4cc[nH]c(=O)c4cc3-c3ccccc3)CC2)c1=O

InChI Key InChIKey=MWKMTMXSHNUORJ-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 431882   

TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Technische UniversitÄT Dortmund

US Patent
LigandPNGBDBM431882(US10550114, Compound 46)
Affinity DataKi:  10.7nMAssay Description:iFLiK and HTRF studies were carried out as described in Z. Fang, J. R. Simard, D. Plenker, H. D. Nguyen, T. Phan, P. Wolle, S. Baumeister, D. Rauh, A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Technische UniversitÄT Dortmund

US Patent
LigandPNGBDBM431882(US10550114, Compound 46)
Affinity DataIC50:  3nMAssay Description:iFLiK and HTRF studies were carried out as described in Z. Fang, J. R. Simard, D. Plenker, H. D. Nguyen, T. Phan, P. Wolle, S. Baumeister, D. Rauh, A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase [E17K](Homo sapiens (Human))
Technische UniversitÄT Dortmund

US Patent
LigandPNGBDBM431882(US10550114, Compound 46)
Affinity DataIC50:  952nMAssay Description:iFLiK and HTRF studies were carried out as described in Z. Fang, J. R. Simard, D. Plenker, H. D. Nguyen, T. Phan, P. Wolle, S. Baumeister, D. Rauh, A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent