BDBM43209 1-(3-methoxyphenyl)-5-(methylsulfonyl)-1H-tetrazole::1-(3-methoxyphenyl)-5-methylsulfonyl-1,2,3,4-tetrazole::1-(3-methoxyphenyl)-5-methylsulfonyltetrazole::5-mesyl-1-(3-methoxyphenyl)tetrazole::MLS000537345::SMR000143783::cid_2221997

SMILES COc1cccc(c1)-n1nnnc1S(C)(=O)=O

InChI Key InChIKey=XIPRBTBTNIAVMG-UHFFFAOYSA-N

Data  3 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 43209   

TargetCell division control protein 42 homolog(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM43209(1-(3-methoxyphenyl)-5-(methylsulfonyl)-1H-tetrazol...)
Affinity DataEC50:  1.54E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDNA damage-inducible transcript 3 protein(Mus musculus)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM43209(1-(3-methoxyphenyl)-5-(methylsulfonyl)-1H-tetrazol...)
Affinity DataIC50:  5.55E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDNA damage-inducible transcript 3 protein(Mus musculus)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM43209(1-(3-methoxyphenyl)-5-(methylsulfonyl)-1H-tetrazol...)
Affinity DataIC50:  5.55E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM43209(1-(3-methoxyphenyl)-5-(methylsulfonyl)-1H-tetrazol...)
Affinity DataEC50:  6.59E+3nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
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TargetX-box-binding protein 1(Homo sapiens (Human))
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM43209(1-(3-methoxyphenyl)-5-(methylsulfonyl)-1H-tetrazol...)
Affinity DataIC50:  1.00E+4nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBcl-2-like protein 11(Homo sapiens (Human))
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM43209(1-(3-methoxyphenyl)-5-(methylsulfonyl)-1H-tetrazol...)
Affinity DataEC50: >3.50E+5nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay