BDBM434530 US10562893, Compound 43

SMILES C[C@H](NCc1ccc2n(c(NC(=O)c3ccns3)nc2c1)-c1cccc(NC(=O)C=C)c1)C(C)(C)C

InChI Key InChIKey=FTVBSMMTSHBKFK-KRWDZBQOSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 434530   

TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
Gb005

US Patent
LigandPNGBDBM434530(US10562893, Compound 43)
Affinity DataEC50: <10nMAssay Description:RLK/TXK: The in vitro kinase assays were performed at Nanosyn utilizing micro-fluidic detection technology. The test compounds were serially pre-dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Gb005

US Patent
LigandPNGBDBM434530(US10562893, Compound 43)
Affinity DataEC50: <10nMAssay Description:ITK: The in vitro kinase assays were performed at Nanosyn utilizing micro-fluidic detection technology. The test compounds were serially pre-diluted ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent