BDBM434531 US10562893, Compound 50

SMILES FC(F)c1ccc(s1)C(=O)Nc1nc2cc(CN3CCOCC3)ccc2n1-c1cccc(NC(=O)C=C)c1

InChI Key InChIKey=YRBQTUHRNLQHKQ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 434531   

TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
Gb005

US Patent
LigandPNGBDBM434531(US10562893, Compound 50)
Affinity DataEC50: <10nMAssay Description:RLK/TXK: The in vitro kinase assays were performed at Nanosyn utilizing micro-fluidic detection technology. The test compounds were serially pre-dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Gb005

US Patent
LigandPNGBDBM434531(US10562893, Compound 50)
Affinity DataEC50: <10nMAssay Description:ITK: The in vitro kinase assays were performed at Nanosyn utilizing micro-fluidic detection technology. The test compounds were serially pre-diluted ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent