BDBM442743 6-Chloro-1-methyl-N-{1-[4-(trifluoromethyl)phenyl]ethyl}-1H-pyrazolo[3,4-d]pyrimidin-4-amine::US10647727, Example 1

SMILES CC(Nc1nc(Cl)nc2n(C)ncc12)c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=ZYAUUUUKFRDVKN-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 442743   

TargetPhosphodiesterase(Macaca mulatta (Rhesus macaque))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM442743(6-Chloro-1-methyl-N-{1-[4-(trifluoromethyl)phenyl]...)
Affinity DataKi:  290nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent