BDBM443223 N-(2-((6-(3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-methylureido)pyrimidin-4-yl)amino)-5-(7-ethyl-2,7-diazaspiro[3.5]nonan-2-yl)phenyl)acrylamide::US10654836, Example 4::US11001572, Example 4
SMILES CCN1CCC2(CN(C2)c2ccc(Nc3cc(ncn3)N(C)C(=O)Nc3c(Cl)c(OC)cc(OC)c3Cl)c(NC(=O)C=C)c2)CC1
InChI Key InChIKey=LGGGGQSCTZIUDU-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 443223
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Zhejiang Hisun Pharmaceutical
US Patent
Zhejiang Hisun Pharmaceutical
US Patent
Affinity DataIC50: 382nMAssay Description:The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Zhejiang Hisun Pharmaceutical
US Patent
Zhejiang Hisun Pharmaceutical
US Patent
Affinity DataIC50: 165nMAssay Description:The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Zhejiang Hisun Pharmaceutical
US Patent
Zhejiang Hisun Pharmaceutical
US Patent
Affinity DataIC50: 439nMAssay Description:The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:The following method was used to determine the inhibition degree of the kinase activity of recombinant human FGFR protein by the compounds of the pre...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Zhejiang Hisun Pharmaceutical
US Patent
Zhejiang Hisun Pharmaceutical
US Patent
Affinity DataIC50: 382nMAssay Description:The following method was used to determine the inhibition degree of the kinase activity of recombinant human FGFR protein by the compounds of the pre...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Zhejiang Hisun Pharmaceutical
US Patent
Zhejiang Hisun Pharmaceutical
US Patent
Affinity DataIC50: 165nMAssay Description:The following method was used to determine the inhibition degree of the kinase activity of recombinant human FGFR protein by the compounds of the pre...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Zhejiang Hisun Pharmaceutical
US Patent
Zhejiang Hisun Pharmaceutical
US Patent
Affinity DataIC50: 439nMAssay Description:The following method was used to determine the inhibition degree of the kinase activity of recombinant human FGFR protein by the compounds of the pre...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...More data for this Ligand-Target Pair