BDBM444934 6-((5-chloro-2-methoxy-4-(2-methoxy-6-((trifluoromethyl)-4-::US10668067, Example 2-6

SMILES CNC(=O)N(c1ccc(cn1)S(=O)(=O)Nc1cccnn1)c1cc(Cl)c(cc1OC)-c1cc(OC)nc(c1)C(F)(F)F

InChI Key InChIKey=NWOLCYSEJDYJLX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 444934   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM444934(6-((5-chloro-2-methoxy-4-(2-methoxy-6-((trifluorom...)
Affinity DataIC50:  26nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent