BDBM444968 6-((carbamoyl(2-chloro-3',5-dimethoxy-5'-(trifluoromethyl)-4-::US10668067, Example 5.4

SMILES COc1cc(cc(c1)C(F)(F)F)-c1cc(OC)c(cc1Cl)N(C(N)=O)c1ccc(cn1)S(=O)(=O)Nc1ccon1

InChI Key InChIKey=WOBPTDHQGPYTCR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 444968   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM444968(6-((carbamoyl(2-chloro-3',5-dimethoxy-5'-(trifluor...)
Affinity DataIC50:  7nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent