BDBM445293 (S)-5-isopropyl-1-(2-((1-(1-(3-(trifluoromethyl)phenyl)-1H-imidazol-4-yl)cyclopropyl)amino)pyrimidine-4-yl)imidazolidine-2-one::US10682352, Compound 22

SMILES CC(C)[C@H]1CNC(=O)N1c1ccnc(NC2(CC2)c2cn(cn2)-c2cccc(c2)C(F)(F)F)n1

InChI Key InChIKey=JMNLNKSAEQOSFD-QGZVFWFLSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 445293   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445293((S)-5-isopropyl-1-(2-((1-(1-(3-(trifluoromethyl)ph...)
Affinity DataIC50: <100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent