BDBM445674 Ex. 12/KM-06-93/(I-12)::US10683309, Example 12::US11028104, Example 12
SMILES CCn1c2nc(Cc3cn4ccccc4n3)n(Cc3ccc(cc3)-c3nc(C)no3)c2c(=O)[nH]c1=O
InChI Key InChIKey=GVYDINLTFQEVNV-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 445674
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin
US Patent
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin
US Patent
Affinity DataIC50: 487nMAssay Description:The full-length coding sequences of human TPH1 and TPH2 were PCR amplified, ligated into a MBP fusion vector (pMalc2x, New England Biolabs, MA, USA) ...More data for this Ligand-Target Pair
TargetTryptophan 5-hydroxylase 2(Homo sapiens (Human))
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin
US Patent
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin
US Patent
Affinity DataIC50: 20nMAssay Description:The full-length coding sequences of human TPH1 and TPH2 were PCR amplified, ligated into a MBP fusion vector (pMalc2x, New England Biolabs, MA, USA) ...More data for this Ligand-Target Pair
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin
US Patent
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin
US Patent
Affinity DataIC50: 487nMAssay Description:The full-length coding sequences of human TPH1 and TPH2 were PCR amplified, ligated into a MBP fusion vector (pMalc2x, New England Biolabs, MA, USA) ...More data for this Ligand-Target Pair
TargetTryptophan 5-hydroxylase 2(Homo sapiens (Human))
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin
US Patent
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin
US Patent
Affinity DataIC50: 20nMAssay Description:The full-length coding sequences of human TPH1 and TPH2 were PCR amplified, ligated into a MBP fusion vector (pMalc2x, New England Biolabs, MA, USA) ...More data for this Ligand-Target Pair