BDBM4459 4-(4-Methylphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile::6,7-dialkoxyquinoline-3-carbonitrile deriv. 22::6,7-dimethoxy-4-[(4-methylphenyl)amino]quinoline-3-carbonitrile

SMILES COc1cc2ncc(C#N)c(Nc3ccc(C)cc3)c2cc1OC

InChI Key InChIKey=JXLUYPNXIHHINO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 4459   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM4459(4-(4-Methylphenylamino)-6,7-dimethoxyquinoline-3-c...)
Affinity DataIC50:  2.75E+3nMAssay Description:Inhibition autophosphorylation of EGFR in human DiFi cells after 2 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM4459(4-(4-Methylphenylamino)-6,7-dimethoxyquinoline-3-c...)
Affinity DataIC50:  2.73E+3nMAssay Description:The EGF-R kinase autophosphorylation activity was measured by DELFIA/time-resolved fluorometry with excitation at 340 nm and emission at 615 nm. Po...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed