BDBM453265 2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-yl)phenoxy)-N-(tert-butyl)acetamide::US10729691, Example 50
SMILES CC(C)(C)NC(=O)COc1cccc(c1)-c1nc2CCOCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1
InChI Key InChIKey=UMCHOTUUCHYZLP-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 453265
TargetSolute carrier family 2, facilitated glucose transporter member 1(Homo sapiens (Human))
Kadmon
US Patent
Kadmon
US Patent
Affinity DataIC50: 55nMAssay Description:HT1080 cells (as well as other cell types) were plated to confluency in 96-well plates. Cells were exposed to the combination of 10 μM Oligomyci...More data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 3(Homo sapiens (Human))
Kadmon
Curated by ChEMBL
Kadmon
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assayMore data for this Ligand-Target Pair
TargetSolute carrier family 2, facilitated glucose transporter member 1(Homo sapiens (Human))
Kadmon
US Patent
Kadmon
US Patent
Affinity DataIC50: 36nMAssay Description:Inhibition of GLUT1 in human wild-type DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assayMore data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Parasite cultures were seeded in 96-well plates (1% hematocrit, 1-2% starting parasitemia, 100 μL total volume) with varying concentrations of t...More data for this Ligand-Target Pair