BDBM454342 US10717734, Compound 18
SMILES CN(C)S(=O)(=O)c1cccc(Cc2c(C)n(C\C(F)=C\CN)c3ccc(C)nc23)c1
InChI Key InChIKey=FVVWNLUUKIPVLO-ZDLGFXPLSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 454342
Affinity DataIC50: >3.00E+5nMAssay Description:LOX and LOXL2: Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen ...More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+3nMAssay Description:MAO-B: The specificity of the compounds of this invention was tested by determining their ability to inhibit MAO-B activities in vitro. Recombinant h...More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+3nMAssay Description:SSAO/VAP-1: Human recombinant SSAO/VAP-1 amine oxidase activity was determined using the coupled colorimetric method as described for monoamine oxida...More data for this Ligand-Target Pair
Affinity DataIC50: <3.00E+5nMAssay Description:LOX and LOXL2: Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen ...More data for this Ligand-Target Pair