BDBM457079 Cis-5-(cyclopropylmethyl)-2- (dimethylamino)-2-(3- fluorophenyl)-7-[2-(oxetan-3- yl)ethyl]-5,7- diazaspiro[3.4]octan-6-one::US10738015, Example SC-47

SMILES CN(C)[C@]1(C[C@@]2(C1)CN(CCC1COC1)C(=O)N2CC1CC1)c1cccc(F)c1

InChI Key InChIKey=SJXAKHTXBBQXBH-ZRZAMGCNSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 457079   

TargetNociceptin receptor(Homo sapiens (Human))
GrÜNenthal

US Patent
LigandPNGBDBM457079(Cis-5-(cyclopropylmethyl)-2- (dimethylamino)-2-(3-...)
Affinity DataKi:  9nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
GrÜNenthal

US Patent
LigandPNGBDBM457079(Cis-5-(cyclopropylmethyl)-2- (dimethylamino)-2-(3-...)
Affinity DataKi:  44nMAssay Description:The hMOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl (pH 7.4)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent