BDBM461263 US10774056, Compound 027::US11542242, Compound 027

SMILES CN1CCN(CC1)c1ccc(cn1)C(=O)Nc1cc(ccc1N)-c1ccncc1

InChI Key InChIKey=SLPPPJJSHXCRPI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 461263   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Regenacy Pharmaceuticals

US Patent
LigandPNGBDBM461263(US10774056, Compound 027 | US11542242, Compound 02...)
Affinity DataIC50: >1.00E+5nMAssay Description:For hERG inhibition assays, the cells used were HEK293 cells stably transfected with hERG (cell line obtained from Cytocentrics Inc. 3463 Magic Drive...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 1A2(Homo sapiens (Human))
Regenacy Pharmaceuticals

US Patent
LigandPNGBDBM461263(US10774056, Compound 027 | US11542242, Compound 02...)
Affinity DataIC50: >1.00E+4nMAssay Description:For Cyp inhibition, human liver microsomes from BD Gentest were incubated with Compound 028 or Compound 032 (10, 3.33, 1.11, 0.37, 0.12, 0.04, 0.01 u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Regenacy Pharmaceuticals

US Patent
LigandPNGBDBM461263(US10774056, Compound 027 | US11542242, Compound 02...)
Affinity DataIC50: >1.00E+5nMAssay Description:For hERG inhibition assays, the cells used were HEK293 cells stably transfected with hERG (cell line obtained from Cytocentrics Inc. 3463 Magic Drive...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 1A2/2C18/2C19(Homo sapiens (Human))
Regenacy Pharmaceuticals

US Patent
LigandPNGBDBM461263(US10774056, Compound 027 | US11542242, Compound 02...)
Affinity DataIC50: >1.00E+4nMAssay Description:For Cyp inhibition, human liver microsomes from BD Gentest were incubated with Compound 028 or Compound 032 (10, 3.33, 1.11, 0.37, 0.12, 0.04, 0.01 &...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent