BDBM461263 US10774056, Compound 027::US11542242, Compound 027
SMILES CN1CCN(CC1)c1ccc(cn1)C(=O)Nc1cc(ccc1N)-c1ccncc1
InChI Key InChIKey=SLPPPJJSHXCRPI-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 461263
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Regenacy Pharmaceuticals
US Patent
Regenacy Pharmaceuticals
US Patent
Affinity DataIC50: >1.00E+5nMAssay Description:For hERG inhibition assays, the cells used were HEK293 cells stably transfected with hERG (cell line obtained from Cytocentrics Inc. 3463 Magic Drive...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:For Cyp inhibition, human liver microsomes from BD Gentest were incubated with Compound 028 or Compound 032 (10, 3.33, 1.11, 0.37, 0.12, 0.04, 0.01 u...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Regenacy Pharmaceuticals
US Patent
Regenacy Pharmaceuticals
US Patent
Affinity DataIC50: >1.00E+5nMAssay Description:For hERG inhibition assays, the cells used were HEK293 cells stably transfected with hERG (cell line obtained from Cytocentrics Inc. 3463 Magic Drive...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:For Cyp inhibition, human liver microsomes from BD Gentest were incubated with Compound 028 or Compound 032 (10, 3.33, 1.11, 0.37, 0.12, 0.04, 0.01 &...More data for this Ligand-Target Pair