BDBM4620 Anilinoquinazoline deriv. 3::N-(4-chlorophenyl)-6,7-dimethoxyquinazolin-4-amine
SMILES COc1cc2ncnc(Nc3ccc(Cl)cc3)c2cc1OC
InChI Key InChIKey=LHGGYEWCVWOGFX-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 4620
Affinity DataIC50: 1.10E+4nMpH: 7.4 T: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu
Curated by ChEMBL
Chaminade University Of Honolulu
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorption by ELISA assay in presence of 20 uM ATPChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMT: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit FGFR-1 TK activity. The compounds were incubated with enzyme 20 min at room ...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chaminade University Of Honolulu
Curated by ChEMBL
Chaminade University Of Honolulu
Curated by ChEMBL
Affinity DataIC50: 800nMT: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room...More data for this Ligand-Target Pair