BDBM466364 (8S)-N-[(1S)-1-(4- cyanophenyl) ethyl]-5-(7H- pyrrolo[2,3- d]pyrimidin-4-yl)- 5-azaspiro [2.5]octane- 8-carboxamide::US10799507, Example 22
SMILES C[C@H](NC(=O)[C@H]1CCN(CC11CC1)c1ncnc2[nH]ccc12)c1ccc(cc1)C#N
InChI Key
Data 4 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 466364
Affinity DataEC50: 1.20nMAssay Description:Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma...More data for this Ligand-Target Pair
Affinity DataEC50: 43.9nMAssay Description:Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma...More data for this Ligand-Target Pair
Affinity DataEC50: 7.10nMAssay Description:Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma...More data for this Ligand-Target Pair
Affinity DataEC50: 3.20nMAssay Description:Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma...More data for this Ligand-Target Pair