BDBM472480 (R)-N-(1-Acryloylpiperidin-3-yl)-5-(*S)-(6-isopropoxy-4-::US10822348, Example 789

SMILES CC(C)Oc1cc(C)c(cn1)-n1c2ccnc3sc(CN[C@@H]4CCCN(C4)C(=O)C=C)c([nH]c1=O)c23

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 472480   

TargetTyrosine-protein kinase BTK [386-659](Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM472480((R)-N-(1-Acryloylpiperidin-3-yl)-5-(*S)-(6-isoprop...)
Affinity DataIC50:  7.94nMAssay Description:A BTK kinase lanthascreen binding assay monitors compound binding to unphosphorylated-BTK kinase domain (UP-BTK), by competing with a fluorescent lab...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent