BDBM476539 US10875854, Example 12
SMILES CC(C)c1ccc(OCC(F)(F)F)n2nc(N[C@H]3[C@H]4CC[C@@H]3CN(C4)c3cc(C)ncn3)nc12
InChI Key InChIKey=MEMLZDLENRRYDO-CWPLJXCYSA-N
Data 1 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 476539
TargetIsoform APP695 of Amyloid-beta precursor protein [K595N,M596L](Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataEC50: 38.5nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair