BDBM476545 (8-endo)-3-(3-methyl-1,2,4-oxadiazol-5-yl)-3-azabicyclo[3.2.1]octan-8-amine::US10875854, Example 18

SMILES CC(C)c1ccc(OCC(F)(F)F)n2nc(N[C@H]3[C@H]4CC[C@@H]3CN(C4)c3nc(C)no3)nc12

InChI Key InChIKey=ISRJHXZPHXHVPI-XOIINTDNSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 476545   

TargetIsoform APP695 of Amyloid-beta precursor protein [K595N,M596L](Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM476545((8-endo)-3-(3-methyl-1,2,4-oxadiazol-5-yl)-3-azabi...)
Affinity DataEC50:  37.4nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent