BDBM481745 N-[1-(1H-indol-3- ylmethyl)pentyl]-2-(4- pyrimidin-2-ylpiperazin-1- yl)thiazole-5-carboxamide::US10913735, Example 2

SMILES CCCCC(Cc1c[nH]c2ccccc12)NC(=O)c1cnc(s1)N1CCN(CC1)c1ncccn1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 481745   

TargetAlpha-synuclein(Homo sapiens (Human))
Ucb Biopharma

US Patent
LigandPNGBDBM481745(N-[1-(1H-indol-3- ylmethyl)pentyl]-2-(4- pyrimidin...)
Affinity DataIC50:  1.00E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent