BDBM484972 US10934302, Example 223

SMILES Cc1c(Sc2ccnc(N)c2Cl)nc2sc(nn12)N1CCC2(Cc3ccccc3[C@H]2N)CC1

InChI Key InChIKey=DQSLYDRJSLICIG-GOSISDBHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 484972   

TargetSH2B adapter protein 2(Human)
Relay Therapeutics

US Patent
LigandPNGBDBM484972(US10934302, Example 223)
Affinity DataIC50: <50nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent