BDBM488138 2-(5-(cyclopropylmethyl)-3- (4-fluoro-3-((2-methylthiazol-5-yl) ethynyl)phenyl)-4-(3-fluoro-4- sulfamoylbenzyl)-1H-pyrazol-1- yl)thiazole-4-carboxylic acid::US10954228, Compound 111

SMILES Cc1ncc(s1)C#Cc1cc(ccc1F)-c1nn(c(CC2CC2)c1Cc1ccc(c(F)c1)[SH+](N)=O)-c1nc(cs1)C(O)=O

InChI Key InChIKey=IZJKUJLROWTEPK-UHFFFAOYSA-O

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 488138   

TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
The Trustees of The University of Pennsylvania

US Patent
LigandPNGBDBM488138(2-(5-(cyclopropylmethyl)-3- (4-fluoro-3-((2-methyl...)
Affinity DataIC50: <100nMAssay Description:Test compounds were placed in a Greiner Bio-One (Monroe, N.C.) 1536-well black solid bottom assay plate. 200 millimolar (mM) Tris HCl, pH 7.4, 100 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent