BDBM488139 2-(5-(cyclopropylmethyl)-4- (3-fluoro-4-sulfamoylbenzyl)-3- (3-((5-methylthiophen-2- yl)ethynyl)phenyl)-1H- pyrazol-1-yl)thiazole-4- carboxylic acid::US10954228, Compound 112::US10961200, Compound 449

SMILES Cc1ccc(s1)C#Cc1cccc(c1)-c1nn(c(CC2CC2)c1Cc1ccc(c(F)c1)[SH+](N)=O)-c1nc(cs1)C(O)=O

InChI Key InChIKey=UFPAYOAGLFERRT-UHFFFAOYSA-O

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 488139   

TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
The Trustees of The University of Pennsylvania

US Patent
LigandPNGBDBM488139(2-(5-(cyclopropylmethyl)-4- (3-fluoro-4-sulfamoylb...)
Affinity DataIC50: <100nMAssay Description:Test compounds were placed in a Greiner Bio-One (Monroe, N.C.) 1536-well black solid bottom assay plate. 200 millimolar (mM) Tris HCl, pH 7.4, 100 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
The Trustees of The University of Pennsylvania

US Patent
LigandPNGBDBM488139(2-(5-(cyclopropylmethyl)-4- (3-fluoro-4-sulfamoylb...)
Affinity DataIC50: <100nMAssay Description:Test compounds were placed in a Greiner Bio-One (Monroe, N.C.) 1536-well black solid bottom assay plate. 200 millimolar (mM) Tris HCl, pH 7.4, 100 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent