BDBM488176 2-(4-(3-fluoro-4-sulfamoylbenzyl)- 3-(3-((5-methylthiophen- 2-yl)ethynyl)phenyl)-5- (spiro[2.2]pentan-1-yl)-1H-pyrazol- 1-yl)thiazole-4-carboxylic acid::US10954228, Compound 131::US11752138, Compound 131
SMILES Cc1ccc(s1)C#Cc1cccc(c1)-c1nn(-c2nc(cs2)C(O)=O)c(C2CC22CC2)c1Cc1ccc(c(F)c1)[SH+](N)=O
InChI Key InChIKey=RODPPELWGFUAKO-UHFFFAOYSA-O
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 488176
Affinity DataIC50: <100nMAssay Description:This example describes a human LDHB biochemical assay employed in the characterization of a compound of Formula I in an embodiment of the dislcosure....More data for this Ligand-Target Pair
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
The Trustees of The University of Pennsylvania
US Patent
The Trustees of The University of Pennsylvania
US Patent
Affinity DataIC50: <100nMAssay Description:Test compounds were placed in a Greiner Bio-One (Monroe, N.C.) 1536-well black solid bottom assay plate. 200 millimolar (mM) Tris HCl, pH 7.4, 100 mi...More data for this Ligand-Target Pair