BDBM488176 2-(4-(3-fluoro-4-sulfamoylbenzyl)- 3-(3-((5-methylthiophen- 2-yl)ethynyl)phenyl)-5- (spiro[2.2]pentan-1-yl)-1H-pyrazol- 1-yl)thiazole-4-carboxylic acid::US10954228, Compound 131::US11752138, Compound 131

SMILES Cc1ccc(s1)C#Cc1cccc(c1)-c1nn(-c2nc(cs2)C(O)=O)c(C2CC22CC2)c1Cc1ccc(c(F)c1)[SH+](N)=O

InChI Key InChIKey=RODPPELWGFUAKO-UHFFFAOYSA-O

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 488176   

TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM488176(2-(4-(3-fluoro-4-sulfamoylbenzyl)- 3-(3-((5-methyl...)
Affinity DataIC50: <100nMAssay Description:This example describes a human LDHB biochemical assay employed in the characterization of a compound of Formula I in an embodiment of the dislcosure....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
The Trustees of The University of Pennsylvania

US Patent
LigandPNGBDBM488176(2-(4-(3-fluoro-4-sulfamoylbenzyl)- 3-(3-((5-methyl...)
Affinity DataIC50: <100nMAssay Description:Test compounds were placed in a Greiner Bio-One (Monroe, N.C.) 1536-well black solid bottom assay plate. 200 millimolar (mM) Tris HCl, pH 7.4, 100 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent