BDBM490784 9-[(4S,6R,7S,11aR,13R,14R,14aR,15R)-13-(6-amino-9H-purin-9-yl)-14-fluoro-2,9,15-trihydroxy-2,9-dioxidooctahydro-11H-4,7-methanofuro[3,2-d][1,3,7,9,2,8]tetraoxadiphosphacyclotridecin-6-yl]-1-methyl-1,9-dihydro-6H-purin-6-one::US10968242, Example 14

SMILES Cn1cnc2n(cnc2c1=O)[C@@H]1C[C@@H]2OP(O)(=O)O[C@@H]3[C@@H](COP(O)(=O)O[C@@H]1[C@@H]2O)O[C@H]([C@@H]3F)n1cnc2c(N)ncnc12

InChI Key InChIKey=BEGKMFFZJBOVOW-PQONOLLKSA-N

Data  1 KI  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 490784   

TargetStimulator of interferon genes protein(Human)
Pfizer

US Patent
LigandPNGBDBM490784(9-[(4S,6R,7S,11aR,13R,14R,14aR,15R)-13-(6-amino-9H...)
Affinity DataKi:  8nMAssay Description:A radioligand binding assay was developed to determine compound interactions were competitive with a tritium-labeled version of the native STING liga...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetStimulator of interferon genes protein [H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM490784(9-[(4S,6R,7S,11aR,13R,14R,14aR,15R)-13-(6-amino-9H...)
Affinity DataKd:  216nMAssay Description:Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetStimulator of interferon genes protein(Human)
Pfizer

US Patent
LigandPNGBDBM490784(9-[(4S,6R,7S,11aR,13R,14R,14aR,15R)-13-(6-amino-9H...)
Affinity DataKd:  15nMAssay Description:Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent