BDBM492545 6-(1-methylethyl)-5-[5- (morpholin-4- ylmethyl)thiophen-2- yl][1,2,4]triazolo[1,5- a]pyrimidin-7(4H)-one::US10975084, Example 11-108

SMILES CC(C)c1c([nH]c2ncnn2c1=O)-c1ccc(CN2CCOCC2)s1

InChI Key InChIKey=XMOCMHNLKIDFTE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 492545   

TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492545(6-(1-methylethyl)-5-[5- (morpholin-4- ylmethyl)thi...)
Affinity DataIC50:  5.08nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent