BDBM493431 US10981917, Example 132

SMILES Cc1c(Br)cnc2n(CCC[C@H]3NCCC[C@@H]3O)cnc12

InChI Key InChIKey=AASQORKGWAXDKN-OLZOCXBDSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 493431   

TargetRibose-phosphate pyrophosphokinase 1(Homo sapiens (Human))
Daewoong Pharmaceutical

US Patent
LigandPNGBDBM493431(US10981917, Example 132)
Affinity DataIC50:  300nMAssay Description:In order to confirm the biological activities of the compounds prepared in Examples, % inhibition or IC50 values of PRS enzyme (phosphoribosylpyropho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent