BDBM494225 (R)-N-(6-(4-cyanopiperidin- 1-yl)-2-(2-fluoro-3-hydroxy- 3-methylbutyl)-1- oxoisoindolin-5- yl)pyrazolo[1,5- a]pyrimidine-3-carboxamide::US10988478, Example 274

SMILES CC(C)(O)[C@H](F)CN1Cc2cc(NC(=O)c3cnn4cccnc34)c(cc2C1=O)N1CCC(CC1)C#N

InChI Key InChIKey=VELXXTVBHCITRO-JOCHJYFZSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 494225   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM494225((R)-N-(6-(4-cyanopiperidin- 1-yl)-2-(2-fluoro-3-hy...)
Affinity DataKi:  1.40nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent