BDBM497357 US11001600, Cmp No. 8::diethyl (3-acetyl-1- (2-((2S,4R)-2-(2'- chloro-2- fluorobiphenyl-3- ylcarbamoyl)-4- fluoropyrrolidin-1- yl)-2-oxoethyl)-5-(2- methylpyrimidin-5- yl)-1H-indol-6- yloxy)methylphosphonate

SMILES CCOP(=O)(COc1cc2n(CC(=O)N3C[C@H](F)C[C@H]3C(=O)Nc3cccc(c3F)-c3ccccc3Cl)cc(C(C)=O)c2cc1-c1cnc(C)nc1)OCC

InChI Key InChIKey=JDLXGOLGRJCEQP-IJAHGLKVSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 497357   

TargetComplement factor D(Homo sapiens (Human))
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM497357(US11001600, Cmp No. 8 | diethyl (3-acetyl-1- (2-((...)
Affinity DataIC50: <1.00E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent