BDBM50000785 2-(3,4-Dichloro-phenyl)-N-methyl-N-(5-oxo-2-pyrrolidin-1-yl-cyclohexyl)-acetamide::CHEMBL74010

SMILES CN([C@H]1CC(=O)CC[C@@H]1N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1

InChI Key InChIKey=PXDHKHOBECBLPH-ROUUACIJSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50000785   

TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50000785(2-(3,4-Dichloro-phenyl)-N-methyl-N-(5-oxo-2-pyrrol...)
Affinity DataKi:  78nMAssay Description:Binding affinity against opioid receptor kappa from guinea pig brain membranes using [3H]ethylketocyclazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50000785(2-(3,4-Dichloro-phenyl)-N-methyl-N-(5-oxo-2-pyrrol...)
Affinity DataKi:  1.30E+4nMAssay Description:Binding affinity against opioid receptor mu from guinea pig brain membranes using [3H]naloxone as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50000785(2-(3,4-Dichloro-phenyl)-N-methyl-N-(5-oxo-2-pyrrol...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity against opioid receptor delta from guinea pig brain membranes using [3H]DADLE as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed